Bromination of Pyridine and Quinoline 1-Oxides
نویسندگان
چکیده
منابع مشابه
Regioselective bromination of fused heterocyclic N-oxides.
A mild method for the regioselective C2-bromination of fused azine N-oxides is presented, employing tosic anhydride as the activator and tetra-n-butylammonium bromide as the nucleophilic bromide source. The C2-brominated compounds are produced in moderate to excellent yields and with excellent regioselectivity in most cases. The potential extension of this method to other halogens, effecting C2...
متن کاملSynthesis and Cytotoxicity of Silicon Containing Pyridine and Quinoline Sulfides
Silicon containing pyridine and quinoline sulfides have been prepared using phase transfer catalytic system thiol/alkyl halide / solid KOH/18-crown-6 / toluene. The target S-ethers were isolated in yields up to 81%. The cytotoxicity of the synthesized compounds was studied. Among pyridine sulfides S-[3-(1-methyl- 1-silacyclohexyl)propyl] derivatives 5e and 6e exhibit the highest cytotoxicity. A...
متن کاملBiodegradation of pyridine and quinoline by two Pseudomonas strains.
OBJECTIVE To study the degradation of pyridine and quinoline by two Pseudomonas. METHODS Based on the analysis of 16S rRNA gene sequence homology and the intergenic spacer region sequence, the two isolates were identified. The degradation capability of pyridine and quinoline was determined according to spectrophotometry and Electrospray Ionisation/Mass Spectrometry (ESI/MS). The degrading pla...
متن کاملCopper(II) Complexes with Organic Ligands (VII) Magnetic Properties of Copper (II) Acetate and Copper (П) Salicylate Complexes of Pyridine and Quinoline N- Oxides
I t is well known tha t copper (I I) acetate monohydrate has a binuclear bridged structure [1, 2] in which two copper atoms are bonded by four acetate groups and the water molecules are linked to copper atoms in axial terminal positions (Fig. 1). The salient feature of this structure is the close approach of the neighbouring copper atoms Cu—Cu = 2.64 Á, owing to which there is direct copper—cop...
متن کاملSynthesis, Characterization and Molecular Docking of Novel Quinoline and Pyridine Derivatives
A new series of substituted quinoline and pyridine derivatives 6a-h are synthesized by the coupling of hydrazide derivatives 4a-b with substituted carboxylic acids 5a-c in the presence of N,N,N’,N’-tetramethyl-o-(benzotriazol-1-yl) uranium tetrafluoroborate TBTU as a coupling agent and lutidine as a base. The newly synthesized compounds 6a–l is characterized by analytical NMR and mass spectral ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1961
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.9.414